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October 01.2025
3 Minutes Read

AI Transforms Autism Diagnosis with Quick ERG Testing Method

AI autism diagnosis ERG child eye examination close-up


Revolutionizing Autism Diagnosis Through AI and ERG Technology

In a groundbreaking development, researchers from the University of South Australia and Flinders University have leveraged artificial intelligence (AI) to develop a faster and more accurate method for diagnosing Autism Spectrum Disorder (ASD) in children using a simple electroretinogram (ERG) test. This innovative approach allows for the diagnosis to be made within approximately ten minutes, utilizing just one bright flash of light delivered to the right eye.

Understanding the Significance of the Research

This study encompassed the retinal responses of 217 children, including 71 with diagnosed ASD and 146 without. The researchers discovered striking differences in the way children's retinas reacted to light: those with ASD exhibited reduced higher frequency components in their retinal signals compared to their neurotypical peers. This finding could represent a significant step forward in the early identification of children on the autism spectrum, providing an avenue for early interventions that can significantly improve quality of life

The Importance of Early Diagnosis

Currently, diagnosing ASD often involves lengthy psychological assessments, which can leave families in limbo and delay essential support and resources. Dr. Fernando Marmolejo-Ramos emphasized how this new test provides a necessary solution to this issue, stating, “This is a massive step because it alleviates time, stress, and money for parents and their children.” Implementing such a rapid and non-invasive test could relieve the substantial burden on families.

AI’s Role in Enhancing Diagnostic Accuracy

The integration of AI into medical diagnostics is gaining traction across various fields, and this research showcases how it plays a critical role in screening for complex conditions like ASD. Paul Constable, a lead researcher, highlighted the excitement surrounding the potential of using retinal signals and machine learning for better diagnostic accuracy. This aligns with the growing trend of technology outsourcing tedious and time-consuming diagnostic processes, allowing clinicians to focus more on patient care rather than administrative hurdles.

Testing for Broader Applications

This initial study, while promising, opens the door for expanded research on younger children and those presenting with different neurodevelopmental disorders, such as Attention Deficit Hyperactivity Disorder (ADHD). Researchers are eager to determine how the electroretinogram might be specific to ASD or how it can be adjusted for other conditions. Hugo Posada-Quintero, a co-researcher, noted the project’s forward momentum: “We will extend the research to look at other cohorts and diagnostic categories, as findings from ERG testing can have wider implications for child psychology.”

Conclusion: The Future of Autism Diagnosis

This pioneering work not only fosters a path for quicker diagnosis but also alleviates some of the strain placed on families navigating the diagnostics and treatment process. As developments continue, the hope is that such technologies can provide earlier and more accurate diagnoses, opening up essential interventions for children who require support. The blend of AI and retinal testing is paving the way for substantial advancements in how we understand and respond to neurodevelopmental disorders. Families and practitioners alike can look forward to the next stage of research that promises to build on these promising discoveries.


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